Human brain may have evolved from two ancient nervous systems, Stanford study finds; forebrain and hindbrain develop from separate cells in 550-million-year-old pattern

A Stanford Medicine study has challenged the traditional understanding of brain development, finding that the forebrain and hindbrain arise from separate progenitor cells. Researchers traced this two-system pattern across 550 million years of evolution, including in chickens, zebrafish and acorn worms. The discovery could help scientists study brainstem diseases and develop better laboratory models.
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